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ICAM1 抗体 (Biotin)

ICAM1 适用: 人 FACS, IHC, BR 宿主: 小鼠 Monoclonal HCD54 Biotin
产品编号 ABIN2661112
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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    小鼠
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    This ICAM1 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Blocking Reagent (BR)
    交叉反应
    Chimpanzee
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    HCD54
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 (ICAM1 产品)
    物质类
    Viral Protein
    背景
    CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 on the cell surface is potently upregulated by activation, a soluble form of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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