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- 抗原 See all PDGFRA 抗体
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PDGFRA antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 产品特性
- The 16A1 monoclonal antibody recognizes human CD140a also known as the platelet-derived growth factor receptor, alpha polypeptide, PDGFR2, and PDGFRα. CD140a is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. The identity of the growth factor bound to the receptor determines whether the functional receptor is a homodimer or heterodimer composed of both PDGFR-α and -β. CD140a contains three immunoglobulin-like domains and a tyrosine kinase domain with a predicted molecular weight of approximately 123 kD. CD140a is widely expressed on a variety of mesenchymal-derived cells and has been implicated in the development of some tumors including basal cell carcinoma and gastric stromal cell tumors. Binding of A-chain containing PDGF molecules as well as protease-activated PDGF-C molecules can stimulate cell proliferation. CD140a has been shown to interact with a number of proteins including CRK, Grb2, Grb14, SHP2, and others as integrin β3, caveolin-1, and nexin sorting molecules. The PDGFRα is heavily phosphorylated on numerous tyrosine residues through both autophosphorylation and ligand-dependent processes. The 16A1 antibody has been shown to be useful for flow cytometric detection of CD140a.
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- 克隆位点
- 16A1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PDGFRA Primary Antibody
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anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibody
PDGFRA 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B11G5 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 361-528) antibodyPDGFRA 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E12F2 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 331-719) antibodyPDGFRA 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-210) antibodyPDGFRA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibodyPDGFRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A10A8 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 698-727) antibodyPDGFRA 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11101 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077) antibodyPDGFRA 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1021-1089) antibodyPDGFRA 适用: 人, 小鼠, 大鼠, 犬 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-1089) antibodyPDGFRA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 25-218) antibodyPDGFRA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H1-1C9 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- 别名
- CD140a (PDGFRA 产品)
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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