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FLT3 抗体 (Biotin)

This anti-FLT3 antibody is a 小鼠 单克隆 antibody detecting FLT3 in FACS. Suitable for 人.
产品编号 ABIN2660938
发货至: 中国

Quick Overview for FLT3 抗体 (Biotin) (ABIN2660938)

抗原

See all FLT3 抗体
FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FLT3 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

BV10A4H2
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

    别名

    CD135

    背景

    CD135 is a 130-160 kD type III tyrosine kinase receptor expressed on CD34+ hematopoietic stem cells, myelomonocytic progenitors, primitive B cell progenitors, and thymocytes. CD135 is also expressed on malignant hematopoietic cells including AML, ALL and CML-BC. CD135, also known as FMS-like tyrosine kinase-3, FLT3, STK-1, and Flk-2, is a growth factor receptor that binds the FLT3 ligand to promote the growth and differentiation of primitive hematopoietic cells. The intracytoplasmic domain of CD135 is modified by phosphorylation and has been shown to interact with Grb2, SOCS1, VAV1, and Shc.

    途径

    RTK signaling
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