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LAMP1 抗体 (Biotin)

This anti-LAMP1 antibody is a 大鼠 单克隆 antibody detecting LAMP1 in FACS. Suitable for 小鼠.
产品编号 ABIN2660905
发货至: 中国

Quick Overview for LAMP1 抗体 (Biotin) (ABIN2660905)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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小鼠

宿主

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大鼠

克隆类型

  • 88
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单克隆

标记

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This LAMP1 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

1D4B
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a

    背景

    CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

    途径

    Autophagy
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