P-Selectin 抗体 (Biotin)
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- 抗原 See all P-Selectin (SELP) 抗体
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This P-Selectin antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 交叉反应
- Chimpanzee
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with Biotin under optimal conditions. The solution is free of unconjugated Biotin.
- 克隆位点
- AK4
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SELP Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
- 别名
- CD62P (SELP 产品)
- 背景
- CD62P is a 140 kD type I transmembrane glycoprotein also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells. CD62 is primarily stored in secretory α-granules in platelets and Weibel-Palade bodies in endothelial cells, and is rapidly relocated to the plasma membrane upon activation. The ligands for CD62P are CD162 and CD24. A primary function of CD62P is cell adhesion during neutrophil rolling, and platelet-neutrophil and platelet-monocyte interactions.
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