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IL-34 抗体 (Biotin)

IL34 适用: 小鼠 ELISA (Detection) 宿主: 山羊 Polyclonal Poly5193 Biotin
产品编号 ABIN2660791
发货至: 中国
  • 抗原 See all IL-34 (IL34) 抗体
    IL-34 (IL34) (Interleukin 34 (IL34))
    适用
    • 38
    • 26
    • 7
    • 1
    • 1
    小鼠
    宿主
    • 52
    • 8
    • 4
    山羊
    克隆类型
    • 56
    • 8
    多克隆
    标记
    • 25
    • 11
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-34 antibody is conjugated to Biotin
    应用范围
    • 48
    • 31
    • 13
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
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    ELISA (Detection)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    Poly5193
    亚型
    Ig Fraction
    Top Product
    Discover our top product IL34 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL-34 (IL34) (Interleukin 34 (IL34))
    别名
    IL-34 (IL34 产品)
    别名
    C16orf77 antibody, IL-34 antibody, 2010004A03Rik antibody, AI593503 antibody, C18H16ORF77 antibody, interleukin 34 antibody, IL34 antibody, Il34 antibody
    背景
    IL-34 is a homodimeric glycoprotein which contains 241 amino acids. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage differentiation, proliferation, and survival. Elevated levels of IL-34 are seen in the plasma of rheumatoid arthritis patients, but can be decreased in response to therapy. IL-34 levels are also increased in the serum of cancer patients and associated with poor prognosis. Mouse IL-34 shares 71 % sequence identity with human IL-34 on the amino acid level.
    途径
    RTK signaling
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