IL-34 抗体 (Biotin)
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- 抗原 See all IL-34 (IL34) 抗体
- IL-34 (IL34) (Interleukin 34 (IL34))
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适用
- 小鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This IL-34 antibody is conjugated to Biotin
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应用范围
- ELISA (Detection)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- 克隆位点
- Poly5193
- 亚型
- Ig Fraction
- Top Product
- Discover our top product IL34 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- IL-34 (IL34) (Interleukin 34 (IL34))
- 别名
- IL-34 (IL34 产品)
- 背景
- IL-34 is a homodimeric glycoprotein which contains 241 amino acids. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage differentiation, proliferation, and survival. Elevated levels of IL-34 are seen in the plasma of rheumatoid arthritis patients, but can be decreased in response to therapy. IL-34 levels are also increased in the serum of cancer patients and associated with poor prognosis. Mouse IL-34 shares 71 % sequence identity with human IL-34 on the amino acid level.
- 途径
- RTK signaling
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