PD-1 抗体 (APC-Cy7)
Quick Overview for PD-1 抗体 (APC-Cy7) (ABIN2660570)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - The antibody was purified by affinity chromatography and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.
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亚型
 - IgG2a kappa
 
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应用备注
 - Optimal working dilution should be determined by the investigator.
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限制
 - 仅限研究用
 
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浓度
 - 0.2 mg/mL
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缓冲液
 - Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from prolonged exposure to light. Do not freeze.
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储存条件
 - 4 °C
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储存方法
 - The antibody solution should be stored undiluted between 2°C and 8°C.
 
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
 - CD279
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背景
 - CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
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途径
 - Cancer Immune Checkpoints
 
抗原
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