NTAN1 抗体
Quick Overview for NTAN1 抗体 (ABIN2660532)
抗原
See all NTAN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯度
- This antibody is at > 85 % purity.
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亚型
- IgM kappa
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anti-N-terminal Asparagine Amidase (NTAN1) (AA 219-310) antibody
NTAN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) antibodyNTAN1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) (AA 1-310) antibodyNTAN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) (AA 1-310) antibodyNTAN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
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别名
- PNAd
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背景
- MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 β1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.
抗原
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