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DC-SIGN/CD209 抗体 (PerCP-Cy5.5)

CD209 适用: 人 FACS 宿主: 小鼠 Monoclonal 9E9A8 PerCP-Cy5.5
产品编号 ABIN2660315
发货至: 中国
  • 抗原 See all DC-SIGN/CD209 (CD209) 抗体
    DC-SIGN/CD209 (CD209) (CD209)
    适用
    • 98
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    宿主
    • 71
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    小鼠
    克隆类型
    • 70
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    单克隆
    标记
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    This DC-SIGN/CD209 antibody is conjugated to PerCP-Cy5.5
    应用范围
    • 68
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    克隆位点
    9E9A8
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD209 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    DC-SIGN/CD209 (CD209) (CD209)
    别名
    CD209 (CD209 产品)
    背景
    CD209, known as Dendritic Cell-Specific Intercellular adhesion molecule 3 (ICAM-3)-Grabbing Nonintegrin (DC-SIGN), is a 44 kD type II transmembrane glycoprotein and a member of the C-type lectin family. CD209 is expressed on myeloid dendritic cells, placental macrophages, liver and placental endothelial cells. CD209 binds to ICAM-3 (CD50), ICAM-2 (CD102), and Butyrophilin (BTN2A1), and mediates dendritic cell migration and T cell proliferation. Importantly, CD209 is a receptor of HIV-1 and some other viruses (such as West Nile virus, hepatitis C virus, etc), and some bacteria or parasites. It plays a criti-cal role in capturing and internalizing those pathogens. LSP1 (leukocyte-specific protein 1) interacts with the cytoplasmic domain of CD209 and mediates transport of HIV to the proteasome.
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