ICOS 抗体 (PerCP-Cy5.5)
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- 抗原 See all ICOS 抗体
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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适用
- 人, 小鼠, 大鼠
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宿主
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仓鼠
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克隆类型
- 单克隆
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标记
- This ICOS antibody is conjugated to PerCP-Cy5.5
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR), Activation (Act)
- 交叉反应
- 猕猴, 猪
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
- 克隆位点
- C398-4A
- 亚型
- IgG
- Top Product
- Discover our top product ICOS Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 别名
- CD278 (ICOS 产品)
- 背景
- ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development.
- 途径
- Cancer Immune Checkpoints
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