C5AR1 抗体 (PE-Cy7)
Quick Overview for C5AR1 抗体 (PE-Cy7) (ABIN2659331)
抗原
See all C5AR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
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亚型
 - IgG2b kappa
 
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应用备注
 - Optimal working dilution should be determined by the investigator.
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限制
 - 仅限研究用
 
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浓度
 - 0.2 mg/mL
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缓冲液
 - Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from prolonged exposure to light. Do not freeze.
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储存条件
 - 4 °C
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储存方法
 - The antibody solution should be stored undiluted between 2°C and 8°C.
 
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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别名
 - CD88
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背景
 - CD88 is a single chain protein with seven membrane-spanning regions and a molecular weight of 43 kD. CD88 is expressed by neutrophils, eosinophils, and monocytes. There have been reports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells, cardiomyocytes, and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteins such as Gi, and after C5a binding, the signal transduced by CD88 results in the activation of PLCβ, PI-3 kinase, and PLA2, among other molecules, resulting in chemotaxis, granule enzyme release, and superoxide anion production.
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途径
 - Complement System
 
抗原
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