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CD46 抗体 (PE-Cy7)

This anti-CD46 antibody is a 小鼠 单克隆 antibody detecting CD46 in FACS. Suitable for 人.
产品编号 ABIN2659285
发货至: 中国

Quick Overview for CD46 抗体 (PE-Cy7) (ABIN2659285)

抗原

See all CD46 抗体
CD46

适用

  • 131
  • 37
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宿主

  • 91
  • 63
  • 2
  • 1
小鼠

克隆类型

  • 79
  • 78
单克隆

标记

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  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CD46 antibody is conjugated to PE-Cy7

应用范围

  • 93
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Flow Cytometry (FACS)

克隆位点

TRA-2-10
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD46

    别名

    CD46

    背景

    CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.

    途径

    Regulation of Actin Filament Polymerization
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