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- 抗原 See all CD276 抗体
- CD276
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD276 antibody is conjugated to PE-Cy7
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
- 克隆位点
- MIH42
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD276 Primary Antibody
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anti-CD276 (CD276) (AA 29-466) antibody
CD276 适用: 人 ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) antibodyCD276 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6A1 unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 101-200) antibodyCD276 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-CD276 (CD276) (AA 29-200) antibodyCD276 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD276
- 别名
- CD276 (CD276 产品)
- 背景
- B7-H3, assigned as CD276, is a type I transmembrane protein and shares 20-27 % amino acid identity with other B7 family members. Human B7-H3 has a single extracellular variable-type immunoglobulin (IgV)-IgC domain, a signature intracellular domain, and an additional isoform, known as 4Ig-B7-H3, containing nearly exact tandem duplication of the IgV-IgC domain and most likely caused by exon duplication. B7-H3 mRNA is broadly expressed in normal tissues whereas its protein expression is relatively rare. The expression of B7-H3 is induced on T cells, natural killer (NK) cells, and antigen-presenting cells (APCs), including dendritic cells (DCs) and macrophages. It can be upregulated during the maturation from monocytes to DCs, or during the interaction between DCs and regulatory T cells. B7-H3 has been shown to be a co-stimulatory molecule that inhibits T-cell responses. B7-H3 has also been identified to bind TLT-2 involved in the intracellular signaling pathway.
- 途径
- Cancer Immune Checkpoints
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