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NGFR 抗体 (PE-Cy7)

This anti-NGFR antibody is a 小鼠 单克隆 antibody detecting NGFR in WB 和 ELISA. Suitable for 人.
产品编号 ABIN2659203
发货至: 中国

Quick Overview for NGFR 抗体 (PE-Cy7) (ABIN2659203)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NGFR antibody is conjugated to PE-Cy7

应用范围

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Western Blotting (WB), ELISA

克隆位点

ME20-4
  • 交叉反应

    猴, Raccoon (Procyon lotor), 绵羊, 猫, 犬, 猪, 兔

    纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    CD271

    背景

    CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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