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IL2 Receptor beta 抗体 (PE-Cy7)

This PE-Cy7-conjugated 大鼠 单克隆 anti-IL2 Receptor beta antibody (Clone TM-beta1) specifically detects IL2 Receptor beta in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2659079
发货至: 中国
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Quick Overview for IL2 Receptor beta 抗体 (PE-Cy7) (ABIN2659079)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

  • 106
  • 91
  • 18
  • 5
  • 1
小鼠

宿主

  • 80
  • 40
  • 37
  • 1
大鼠

克隆类型

  • 79
  • 77
  • 2
单克隆

标记

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This IL2 Receptor beta antibody is conjugated to PE-Cy7

应用范围

  • 84
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Flow Cytometry (FACS)

克隆位点

TM-beta1
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    CD122

    物质类

    Chemical

    背景

    CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit(CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

    途径

    JAK/STAT Signaling, Growth Factor Binding
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