IL2 Receptor beta 抗体 (PE-Cy7)
Quick Overview for IL2 Receptor beta 抗体 (PE-Cy7) (ABIN2659079)
抗原
See all IL2 Receptor beta (IL2RB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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别名
- CD122
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物质类
- Chemical
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背景
- CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit(CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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