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ICOS 抗体 (PE-Cy5)

ICOS 适用: 小鼠 CyTOF, ELISA (Capture) 宿主: 仓鼠 Monoclonal 15F9 PE-Cy5
产品编号 ABIN2658951
发货至: 中国
  • 抗原 See all ICOS 抗体
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    适用
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    小鼠
    宿主
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    仓鼠
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    单克隆
    标记
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    This ICOS antibody is conjugated to PE-Cy5
    应用范围
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    Cytometry by Time of Flight (CyTOF), ELISA (Capture)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE/Cy5 under optimal conditions. The solution is free of unconjugated PE/Cy5 and unconjugated antibody.
    克隆位点
    15F9
    亚型
    IgG
    Top Product
    Discover our top product ICOS Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    别名
    CD278 (ICOS 产品)
    别名
    ICOS antibody, AILIM antibody, CCLP antibody, CRP-1 antibody, H4 antibody, Ly115 antibody, CD278 antibody, CVID1 antibody, Ailim antibody, inducible T-cell costimulator antibody, inducible T cell co-stimulator antibody, inducible T-cell co-stimulator antibody, ICOS antibody, LOC100232284 antibody, Icos antibody
    背景
    CD278 is a 47-57 kD protein, also known as inducible costimulatory molecule (ICOS), or H4. This protein is homologous to the CD28/CTLA-4 proteins. It forms homodimers and is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS has been shown to be involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. It has also been shown to be involved in airway tolerance and the downregulation of pulmonary inflammation.
    途径
    Cancer Immune Checkpoints
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