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CD80 抗体 (APC)

This anti-CD80 antibody is a 仓鼠 单克隆 antibody detecting CD80 in ICFC. Suitable for 小鼠.
产品编号 ABIN2658718
发货至: 中国

Quick Overview for CD80 抗体 (APC) (ABIN2658718)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

  • 104
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  • 1
仓鼠

克隆类型

  • 168
  • 81
  • 2
单克隆

标记

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  • 1
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This CD80 antibody is conjugated to APC

应用范围

  • 129
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Intracellular Flow Cytometry (ICFC)

克隆位点

16-10A1
  • 交叉反应

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD80

    别名

    CD80

    背景

    CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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