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BST2 抗体 (APC)

This anti-BST2 antibody is a 小鼠 单克隆 antibody detecting BST2 in FACS. Suitable for 人.
产品编号 ABIN2658186
发货至: 中国

Quick Overview for BST2 抗体 (APC) (ABIN2658186)

抗原

See all BST2 抗体
BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

适用

  • 85
  • 33
  • 11
  • 1

宿主

  • 69
  • 15
  • 2
  • 1
小鼠

克隆类型

  • 55
  • 32
单克隆

标记

  • 40
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This BST2 antibody is conjugated to APC

应用范围

  • 61
  • 34
  • 26
  • 24
  • 15
  • 14
  • 14
  • 13
  • 9
  • 6
  • 1
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Flow Cytometry (FACS)

克隆位点

RS38E
  • 交叉反应

    Pigtailed Macaque, 猕猴

    纯化方法

    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

    别名

    CD317

    背景

    CD317, also known as BST2, Tetherin, and HM1.24, is a type II transmembrane GPI-protein with a molecular weight of about 29-33 kD. It is an interferon-induced protein expressed on dendritic cells, plasma cells, B lymphoblast cells, monocytes, granulocytes, T cells, NK cells, stromal cells, and some non-hematopoietic cells. BST2 inhibits cytokine production through interaction with ILT7 (CD85g). It is also involved in the regulation of B cell growth. More importantly, BST2 has been found to restrict the release of a number of viruses from infected cells, including all tested retroviruses (such as HIV-1) and some arenaviruses and filoviruses. In HIV-1 studies, it has been reported that BST2 retains the nascent virons on the surface of infected cells by incorporation of the protein into HIV-1 particles. HIV-1 Vpu is able to induce BST2 degradation.

    途径

    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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