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Interleukin 17a 抗体 (Alexa Fluor 700)

This Alexa Fluor 700-conjugated 大鼠 单克隆 anti-Interleukin 17a antibody (Clone TC11-18H10-1) specifically detects Interleukin 17a in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2658105
发货至: 中国
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Quick Overview for Interleukin 17a 抗体 (Alexa Fluor 700) (ABIN2658105)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

  • 104
  • 56
  • 19
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
小鼠

宿主

  • 60
  • 54
  • 20
  • 15
  • 5
  • 2
大鼠

克隆类型

  • 90
  • 65
  • 1
单克隆

标记

  • 80
  • 19
  • 18
  • 13
  • 10
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Interleukin 17a antibody is conjugated to Alexa Fluor 700

应用范围

  • 72
  • 52
  • 42
  • 18
  • 15
  • 11
  • 10
  • 8
  • 8
  • 7
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

TC11-18H10-1
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 700 under optimal conditions.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A

    背景

    IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
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