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CD80 抗体 (Alexa Fluor 647)

This Alexa Fluor 647-conjugated 小鼠 单克隆 anti-CD80 antibody (Clone 2D10) specifically detects CD80 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN2657847
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for CD80 抗体 (Alexa Fluor 647) (ABIN2657847)

抗原

See all CD80 抗体
CD80

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD80 antibody is conjugated to Alexa Fluor 647

应用范围

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Flow Cytometry (FACS)

克隆位点

2D10
  • 交叉反应

    猕猴

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    CD80

    别名

    CD80

    背景

    CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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