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BST2 抗体 (Alexa Fluor 647)

BST2 适用: 小鼠 FACS, IEM 宿主: 大鼠 Monoclonal 129c1 Alexa Fluor 647
产品编号 ABIN2657750
发货至: 中国
  • 抗原 See all BST2 抗体
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    适用
    • 60
    • 31
    • 11
    • 1
    小鼠
    宿主
    • 51
    • 8
    • 1
    大鼠
    克隆类型
    • 46
    • 14
    单克隆
    标记
    • 32
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BST2 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 51
    • 22
    • 20
    • 14
    • 14
    • 13
    • 12
    • 11
    • 9
    • 6
    • 1
    Flow Cytometry (FACS), Immunoelectron Microscopy (IEM)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    129c1
    亚型
    IgG2b kappa
    Top Product
    Discover our top product BST2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    别名
    CD317 (BST2 产品)
    别名
    BST2 antibody, CD317 antibody, TETHERIN antibody, 2310015I10Rik antibody, Bst-2 antibody, C87040 antibody, DAMP-1 antibody, GREG antibody, Damp1 antibody, bone marrow stromal cell antigen 2 antibody, bone marrow stromal antigen 2 antibody, BST2 antibody, LOC618737 antibody, Bst2 antibody
    背景
    CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1, is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantly expressed on Type I IFN-producing cells (IPCs) in naive mice, but is up-regulated on most cell types following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminally differentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiple myeloma, renal cell carcinoma, and melanoma cells. BST2 was recently identified as an IFN-induced cellular response factor that blocks release of HIV-1 and other retroviruses from infected cells. BST2 has been found to be the natural ligand of ILT7 in human model.
    途径
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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