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ICOS 抗体 (Alexa Fluor 647)

This anti-ICOS antibody is a 仓鼠 单克隆 antibody detecting ICOS in FACS 和 ICFC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2657721
发货至: 中国

Quick Overview for ICOS 抗体 (Alexa Fluor 647) (ABIN2657721)

抗原

See all ICOS 抗体
ICOS (Inducible T-Cell Co-Stimulator (ICOS))

适用

  • 94
  • 32
  • 27
  • 5
人, 小鼠, 大鼠

宿主

  • 85
  • 19
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
仓鼠

克隆类型

  • 81
  • 32
  • 1
单克隆

标记

  • 53
  • 17
  • 8
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ICOS antibody is conjugated to Alexa Fluor 647

应用范围

  • 72
  • 42
  • 33
  • 32
  • 19
  • 15
  • 14
  • 13
  • 9
  • 8
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

克隆位点

C398-4A
  • 交叉反应

    猕猴, 猪

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    ICOS (Inducible T-Cell Co-Stimulator (ICOS))

    别名

    CD278

    背景

    ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development.

    途径

    Cancer Immune Checkpoints
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