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CD226 抗体 (Alexa Fluor 647)

CD226 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal TX42-1 Alexa Fluor 647
产品编号 ABIN2657698
发货至: 中国
  • 抗原 See all CD226 抗体
    CD226
    适用
    • 68
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 51
    • 19
    • 3
    大鼠
    克隆类型
    • 47
    • 25
    • 1
    单克隆
    标记
    • 43
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD226 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 40
    • 30
    • 25
    • 13
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    TX42-1
    亚型
    IgG2a
    Top Product
    Discover our top product CD226 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    CD226
    别名
    CD226 (CD226 产品)
    别名
    CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody
    背景
    Mouse CD226 (DNAM-1) is a 65 kd glycoprotein of a member of Ig super-family adhesion molecule containing 2 immunoglobulin-like domains. It is associated with leukocyte function associated antigen-1 (LFA-1) involving in TCR-mediated signal transduction for T cell proliferation and differentiation. CD226 is also involved in NK cell and T cell mediated cytotoxicity against certain tumors. CD226 (DNAM-1) is constitutively expressed on naive CD8+ and CD4+ T cells, macrophages, and NK cells. It was reported that CD226 expression is up-regulated on Th1 cells, but down-regulated on Th2 and Th0 cells. CD155 and CD112 are the ligands for CD226.
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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