CXCR1 抗体 (Alexa Fluor 488)
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- 抗原 See all CXCR1 抗体
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CXCR1 antibody is conjugated to Alexa Fluor 488
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
- 克隆位点
- 8F1-CXCR1
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product CXCR1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- 别名
- CD181 (CXCR1 产品)
- 背景
- CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor that belongs to the G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower than that of CXCR2. CXCR1 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α(CXCL1).
- 途径
- cAMP Metabolic Process
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