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IKZF1 抗体 (Alexa Fluor 647)

This anti-IKZF1 antibody is a 小鼠 单克隆 antibody detecting IKZF1 in FACS. Suitable for 小鼠.
产品编号 ABIN2657210
发货至: 中国

Quick Overview for IKZF1 抗体 (Alexa Fluor 647) (ABIN2657210)

抗原

See all IKZF1 抗体
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

适用

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小鼠

宿主

  • 60
  • 12
  • 2
小鼠

克隆类型

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  • 16
单克隆

标记

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This IKZF1 antibody is conjugated to Alexa Fluor 647

应用范围

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Flow Cytometry (FACS)

克隆位点

2A9-Ikaros
  • 无交叉反应

    小鼠

    纯化方法

    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG1 kappa, IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    别名

    Ikaros

    背景

    Ikaros family members, including Ikaros and Helios, play a role in the development of lymphocytes and B and T cells. They are nuclear factors that colocalize with DNA replication machinery components in higher-order chromatin structures and respond to signaling events, such as T cell activation. Helios and Ikaros bind to similar DNA sequences, and they function as hemopoietic-specific transcription factors. Members of the Ikaros family contain zinc-finger domains that are involved in DNA-binding and in the formation of homodimers and heterodimers between Ikaros family members. Expression of Ikaros is primarily detected in the thymus and spleen, where it is essential for regulating T cell specific gene transcription and for the differentiation and commitment of early hemopoietic progenitors to the B and T lymphoid lineages. Ikaros and Helios also appear to regulate cell cycle entry by inducing transcriptional repression under varying conditions and, thereby, mediate T cell activation and IL-2 mediated signaling events.

    途径

    Production of Molecular Mediator of Immune Response
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