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BST2 抗体 (Alexa Fluor 647)

BST2 适用: 人 ELISA 宿主: 小鼠 Monoclonal RS38E Alexa Fluor 647
产品编号 ABIN2657173
发货至: 中国
  • 抗原 See all BST2 抗体
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    适用
    • 60
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    宿主
    • 51
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BST2 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 51
    • 22
    • 20
    • 14
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    • 13
    • 12
    • 11
    • 9
    • 6
    • 1
    ELISA
    交叉反应
    Pigtailed Macaque, 猕猴
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    RS38E
    亚型
    IgG1 kappa
    Top Product
    Discover our top product BST2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    别名
    CD317 (BST2 产品)
    别名
    BST2 antibody, CD317 antibody, TETHERIN antibody, 2310015I10Rik antibody, Bst-2 antibody, C87040 antibody, DAMP-1 antibody, GREG antibody, Damp1 antibody, bone marrow stromal cell antigen 2 antibody, bone marrow stromal antigen 2 antibody, BST2 antibody, LOC618737 antibody, Bst2 antibody
    背景
    CD317, also known as BST2, Tetherin, and HM1.24, is a type II transmembrane GPI-protein with a molecular weight of about 29-33 kD. It is an interferon-induced protein expressed on dendritic cells, plasma cells, B lymphoblast cells, monocytes, granulocytes, T cells, NK cells, stromal cells, and some non-hematopoietic cells. BST2 inhibits cytokine production through interaction with ILT7 (CD85g). It is also involved in the regulation of B cell growth. More importantly, BST2 has been found to restrict the release of a number of viruses from infected cells, including all tested retroviruses (such as HIV-1) and some arenaviruses and filoviruses. In HIV-1 studies, it has been reported that BST2 retains the nascent virons on the surface of infected cells by incorporation of the protein into HIV-1 particles. HIV-1 Vpu is able to induce BST2 degradation.
    途径
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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