FGFR2 抗体
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Quick Overview for FGFR2 抗体 (ABIN265417)
抗原
See all FGFR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of FGFR2 protein. (region surrounding Val501)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-51), (N-Term) antibody
FGFR2 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01567 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 1-100) antibodyFGFR2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 621-723) antibodyFGFR2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) antibodyFGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB17696 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37) antibodyFGFR2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 245-345) antibodyFGFR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibodyFGFR2 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB15689 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 21-120) antibodyFGFR2 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (C-Term) antibodyFGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-368) antibodyFGFR2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000approx. 1/20000Western Blot: 1/500approx. 1/1000Immunohistochemistry (Paraffin): 1/50approx. 1/200
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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别名
- CD332 / FGFR-2
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背景
- Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors.These include the Flg receptor or FGFR-1, the Bek receptor (or FGFR-2), FGFR-3, FGFR- 4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligandbinding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The gene encoding human Bek (also esignated K-sam) maps to chromosome 10q26 and is alternatively spliced to produce several isoforms. Heterogeneous mutations in Bek are associated with a range of craniosynostosis syndromes including Pfeiffer syndrome, Crouzon syndrome, Jackson-Weiss syndrome and Apert syndrome.Synonyms: BEK, FGFR2, Fibroblast growth factor receptor 2, KGFR, KSAM, Keratinocyte growth factor receptor 2
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分子量
- approx. 92, 145 kDa
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基因ID
- 2263
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NCBI登录号
- NP_000132
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UniProt
- P21802
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
抗原
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