E2F6 抗体
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北京 101111
Quick Overview for E2F6 抗体 (ABIN265390)
抗原
See all E2F6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of E2F6 protein (region surrounding Glu170).
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-E2F Transcription Factor 6 (E2F6) (Internal Region) antibody
E2F6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) antibodyE2F6 适用: 人 WB, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) antibodyE2F6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F7-A9 unconjugated
anti-E2F Transcription Factor 6 (E2F6) antibodyE2F6 适用: 人, 小鼠 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (Internal Region) antibodyE2F6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 43-92) antibodyE2F6 适用: 人, 小鼠, Pig, 犬, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- E2F6 (E2F Transcription Factor 6 (E2F6))
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别名
- E2F6
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背景
- The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an Synonyms: E2F transcription factor 6, E2F-6, MGC111545, Transcription factor E2F6
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分子量
- approx. 31 kDa
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基因ID
- 1876
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NCBI登录号
- NP_937987
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UniProt
- O75461
抗原
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