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Claudin 4 抗体

CLDN4 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265363
发货至: 中国
  • 抗原 See all Claudin 4 (CLDN4) 抗体
    Claudin 4 (CLDN4)
    适用
    • 70
    • 30
    • 26
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 62
    • 10
    克隆类型
    • 62
    • 10
    多克隆
    标记
    • 35
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 4 antibody is un-conjugated
    应用范围
    • 58
    • 34
    • 13
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Claudin 4 protein. (region surrounding Pro192)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product CLDN4 Primary Antibody
  • 应用备注
    ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Claudin 4 (CLDN4)
    别名
    Claudin-4 / CLDN4 (CLDN4 产品)
    别名
    CPE-R antibody, CPER antibody, CPETR antibody, CPETR1 antibody, WBSCR8 antibody, hCPE-R antibody, Cep-r antibody, Cpetr antibody, Cpetr1 antibody, CLDN4 antibody, cper antibody, cpe-r antibody, cpetr antibody, cpetr1 antibody, hcpe-r antibody, wbscr8 antibody, claudin 4 antibody, claudin 4 L homeolog antibody, CLDN4 antibody, Cldn4 antibody, cldn4 antibody, cldn4.L antibody
    背景
    The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23Synonyms: CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein
    分子量
    approx. 22 kDa
    基因ID
    1364
    NCBI登录号
    NP_001296
    UniProt
    O14493
    途径
    Hepatitis C
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