Claudin 4 抗体
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北京 101111
Quick Overview for Claudin 4 抗体 (ABIN265363)
抗原
See all Claudin 4 (CLDN4) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Claudin 4 protein. (region surrounding Pro192)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Claudin 4 (CLDN4) (AA 21-120) antibody
CLDN4 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) (C-Term) antibodyCLDN4 适用: 人, 大鼠, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Claudin 4 (CLDN4) (AA 29-78) antibodyCLDN4 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-Claudin 4 (CLDN4) (AA 1-209) antibodyCLDN4 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) (C-Term) antibodyCLDN4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) antibodyCLDN4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) (C-Term) antibodyCLDN4 适用: 人, 小鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) (C-Term) antibodyCLDN4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) (Ser255) antibodyCLDN4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 4 (CLDN4) (AA 29-78) antibodyCLDN4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A4 unconjugated
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应用备注
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ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Claudin 4 (CLDN4)
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别名
- Claudin-4 / CLDN4
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背景
- The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23Synonyms: CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein
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分子量
- approx. 22 kDa
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基因ID
- 1364
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NCBI登录号
- NP_001296
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UniProt
- O14493
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途径
- Hepatitis C
抗原
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