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Claudin 2 抗体

CLDN2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265361
发货至: 中国
  • 抗原 See all Claudin 2 (CLDN2) 抗体
    Claudin 2 (CLDN2)
    适用
    • 98
    • 18
    • 15
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 95
    • 4
    克隆类型
    • 93
    • 6
    多克隆
    标记
    • 38
    • 12
    • 10
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Claudin 2 antibody is un-conjugated
    应用范围
    • 71
    • 64
    • 48
    • 25
    • 11
    • 7
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Claudin 2 protein.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product CLDN2 Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Claudin 2 (CLDN2)
    别名
    Claudin-2 / CLDN2 (CLDN2 产品)
    别名
    CLDN2 antibody, zgc:92260 antibody, AL022813 antibody, RGD1560247 antibody, claudin 2 antibody, CLDN2 antibody, cldn2 antibody, Cldn2 antibody
    背景
    The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Synonyms: CLD2, SP82
    分子量
    approx. 25 kDa
    基因ID
    9075
    NCBI登录号
    NP_001164563
    UniProt
    P57739
    途径
    Hepatitis C
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