GLI1 抗体
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- 抗原 See all GLI1 抗体
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Thia antibody detects Zinc Finger Protein GLI1, found in testis, myometrium and fallopian tube.
- 纯化方法
- Purified
- 免疫原
- Synthetic peptide derived from human zinc finger protein GLI1
- Top Product
- Discover our top product GLI1 Primary Antibody
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- 应用备注
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Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- 抗原
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- 别名
- GLI1 (GLI1 产品)
- 背景
- Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes dring normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.Synonyms: GLI, GLI-1, Glioma-associated oncogene, Oncogene GLI, Zinc finger protein GLI1
- 基因ID
- 2735
- NCBI登录号
- NP_001153517
- UniProt
- P08151
- 途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
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