SMPD3 抗体
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北京 101111
Quick Overview for SMPD3 抗体 (ABIN265269)
抗原
See all SMPD3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Sphingomyelin Phosphodiesterase 3.
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纯化方法
- Purified
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免疫原
- Synthetic peptide derived from human sphingomyelin phosphodiesterase 3
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应用备注
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Western blot (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
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别名
- SMPD3
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背景
- Sphingomyelin phosphodiesterase 3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these two cellular events independently. It also hydrolyzes sphingosylphosphocholine. Sphingomyelin phosphodiesterase 3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It likely acts as a regulator of postnatal development and participates in bone and dentin mineralization. It is activated by unsaturated fatty acids and phosphatidylserine. it is predominantly expressed in the brain.Synonyms: Neutral sphingomyelinase 2, Neutral sphingomyelinase II, Sphingomyelin phosphodiesterase 3
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基因ID
- 55512
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NCBI登录号
- NP_061137
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UniProt
- Q9NY59
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途径
- Hormone Transport
抗原
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