TLR5 抗体 (Middle Region)
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Quick Overview for TLR5 抗体 (Middle Region) (ABIN265143)
抗原
See all TLR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects TLR5. Found in the membrane, TLR5 is hghly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis (6).
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纯化方法
- Purified
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免疫原
- Peptide corresponding to 16 amino acids near the center of human TLR5
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亚型
- IgG
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anti-Toll-Like Receptor 5 (TLR5) (AA 325-644) antibody
TLR5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 303-514) antibodyTLR5 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 8-1# unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 700-800) antibodyTLR5 适用: 人, 小鼠 WB, IHC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 19D759-2 unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 682-850) antibodyTLR5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 701-810) antibodyTLR5 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 46-205) antibodyTLR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 517-634) antibodyTLR5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Toll-Like Receptor 5 (TLR5) (C-Term) antibodyTLR5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1 to 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- TLR5 (Toll-Like Receptor 5 (TLR5))
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别名
- TLR5
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背景
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-κB, leading to the activation of TNF-? and other cytokines (4). A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires' disease and demonstrates the importance of TLR5 in the innate immune response (5).Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
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基因ID
- 7100
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NCBI登录号
- NP_003259
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UniProt
- O60602
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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