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TICAM2 抗体 (C-Term)

This anti-TICAM2 antibody is a 兔 多克隆 antibody detecting TICAM2 in WB 和 IHC (fro). Suitable for 人.
产品编号 ABIN265137
发货至: 中国

Quick Overview for TICAM2 抗体 (C-Term) (ABIN265137)

抗原

See all TICAM2 抗体
TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

适用

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宿主

  • 46
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克隆类型

  • 50
多克隆

标记

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This TICAM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to Toll-like Receptor Adaptor Protein (TIRP) (CT).

    纯化方法

    Purified

    免疫原

    Rabbit polyclonal TIRP antibody was raised against a peptide corresponding to amino acids at the C-terminus of human TIRP.

    亚型

    IgG
  • 应用备注

    Western Blot: 0.5 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原

    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

    别名

    TICAM2 / TRAM

    背景

    TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1 - 3). TLRs are signaling molecules that recognize different pathogenassociated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-?B (5). Expression of TIRP appears to be essential for TLR4 signalling (6).Synonyms: Putative NF-kappa-B-activating protein 502, TICAM-2, TIR domain-containing adapter molecule 2, TIRAP3, TIRP, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein

    基因ID

    100302736

    NCBI登录号

    NP_001157941

    UniProt

    Q86XR7

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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