LY86 抗体 (C-Term)
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Quick Overview for LY86 抗体 (C-Term) (ABIN265131)
抗原
See all LY86 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to Lymphocyte Antigen 86/MD-1.
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纯化方法
- Purified
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免疫原
- Rabbit polyclonal MD-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human MD-1
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亚型
- IgG
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anti-Lymphocyte Antigen 86 (LY86) (AA 21-162) antibody
LY86 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 86 (LY86) (AA 112-125) antibodyLY86 适用: 人, 小鼠 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 86 (LY86) (AA 1-162) antibodyLY86 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Lymphocyte Antigen 86 (LY86) (AA 26-125) antibodyLY86 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Lymphocyte Antigen 86 (LY86) (AA 50-150) antibodyLY86 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 86 (LY86) (Center) antibodyLY86 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 86 (LY86) (C-Term) antibodyLY86 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 86 (LY86) (AA 97-127), (C-Term) antibodyLY86 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0,5 - 1 μg/mL. May cooperate with CD180 and TLR4 to mediate the innate immune response to bacteriallipopolysaccharide (LPS) and cytokine production. Important for efficie nt CD180 cellsurface expression.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- LY86 (Lymphocyte Antigen 86 (LY86))
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别名
- LY86 / MD-1
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背景
- Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1
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基因ID
- 9450
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NCBI登录号
- NP_004262
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UniProt
- O95711
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途径
- Toll-Like Receptors Cascades
抗原
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