TYROBP 抗体
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北京 101111
Quick Overview for TYROBP 抗体 (ABIN265057)
抗原
See all TYROBP 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is specific to DAP12.
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纯化方法
- Purified
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免疫原
- Recombinant DAP12 protein.
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应用备注
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Western Blot. Immunoprecipitation: Use 2-4 μg/mL of protein lysate. Positive Control: NKp44 positive cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS, 0.08 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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别名
- TYROBP / DAP12
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背景
- DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells (1,2). DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction (3). Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice (4,5), as well as presenile dementia and bone cysts in humans (6).Synonyms: DNAX-activation protein 12, KARAP, Killer-activating receptor-associated protein, TYRO protein tyrosine kinase-binding protein
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基因ID
- 7305
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NCBI登录号
- NP_003323
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UniProt
- O43914
抗原
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