VSX2 抗体 (N-Term)
(11 references)Quick Overview for VSX2 抗体 (N-Term) (ABIN265011)
抗原
See all VSX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-131, N-Term
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特异性
- This antibody recognizes chx 10 (N-Term).
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纯化方法
- Purified
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免疫原
- Antibody raised against a recombinant protein corresponding to amino acids 1 to 131 derived from the N terminal of the human Chx10 protein conjugated to GST.
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亚型
- IgG
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anti-Visual System Homeobox 2 (VSX2) (N-Term) antibody
VSX2 适用: 人 WB, IHC (fro) 宿主: 绵羊 Polyclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) (C-Term) antibodyVSX2 适用: 人 WB, IHC (fro) 宿主: 绵羊 Polyclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) (Internal Region) antibodyVSX2 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) (AA 1-361) antibodyVSX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) (AA 234-283) antibodyVSX2 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) antibodyVSX2 适用: 人, 小鼠, 大鼠 WB 宿主: 绵羊 Polyclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) antibodyVSX2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Visual System Homeobox 2 (VSX2) (AA 264-361), (C-Term) antibodyVSX2 适用: 小鼠, 大鼠 WB, IHC (fro) 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5-1.0 mg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.08 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C. Can be shipped at ambient temperature.
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: "Birth of cone bipolar cells, but not rod bipolar cells, is associated with existing RGCs." in: PLoS ONE, Vol. 9, Issue 1, pp. e83686, (2014) (PubMed).
: "Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration." in: Nature communications, Vol. 4, pp. 2312, (2013) (PubMed).
: "Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome." in: PLoS ONE, Vol. 8, Issue 3, pp. e59306, (2013) (PubMed).
: "Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 9, pp. E553-62, (2012) (PubMed).
: "Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2." in: PLoS ONE, Vol. 7, Issue 6, pp. e39702, (2012) (PubMed).
: "Prolonged expression of Puma in cholinergic amacrine cells during the development of rat retina." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 60, Issue 10, pp. 777-88, (2012) (PubMed).
: "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." in: Nature cell biology, Vol. 14, Issue 9, pp. 958-65, (2012) (PubMed).
: "Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 46, pp. 12707-20, (2007) (PubMed).
: "Wnt signaling promotes regeneration in the retina of adult mammals." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 15, pp. 4210-9, (2007) (PubMed).
: "LPA2 receptor mediates mitogenic signals in human colon cancer cells." in: American journal of physiology. Cell physiology, Vol. 289, Issue 1, pp. C2-11, (2005) (PubMed).
: "Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3500-7, (2003) (PubMed).
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: "Birth of cone bipolar cells, but not rod bipolar cells, is associated with existing RGCs." in: PLoS ONE, Vol. 9, Issue 1, pp. e83686, (2014) (PubMed).
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- VSX2 (Visual System Homeobox 2 (VSX2))
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别名
- VSX2 / CHX10
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背景
- Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.Synonyms: Ceh-10 homeodomain-containing homolog, HOX10, Homeobox protein CHX10, Visual system homeobox 2
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分子量
- 46 kDa
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基因ID
- 12677
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NCBI登录号
- NP_031727
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UniProt
- Q61412
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途径
- Dopaminergic Neurogenesis
抗原
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