BACE2 抗体 (AA 496-511)
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- 抗原 See all BACE2 抗体
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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抗原表位
- AA 496-511
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BACE2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to BACE 2 (CT).
- 纯化方法
- Purified
- 免疫原
- Synthetic peptide corresponding to amino acids 496 to 511 of human BACE2
- 亚型
- IgG
- Top Product
- Discover our top product BACE2 Primary Antibody
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anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 230-396) antibody
BACE2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 242-502) antibodyBACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 240-470) antibodyBACE2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 156-407) antibodyBACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 84-157) antibodyBACE2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 44-59) antibodyBACE2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) antibodyBACE2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 1-9 unconjugated Recombinant Antibody
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 336-365) antibodyBACE2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 101-200) antibodyBACE2 适用: 大鼠 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 306-395) antibodyBACE2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Western Blot: 0.5 to 1 μg/mL. Detects an approximately 70 kDa band in human heart tissuelysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- 抗原
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
- 别名
- BACE2 (BACE2 产品)
- 别名
- AEPLC antibody, ALP56 antibody, ASP1 antibody, ASP21 antibody, BAE2 antibody, CEAP1 antibody, DRAP antibody, 1110059C24Rik antibody, AI850424 antibody, ARP1 antibody, CDA13 antibody, beta-site APP-cleaving enzyme 2 antibody, BACE2 antibody, Bace2 antibody
- 背景
- Accumulation of the amyloid-b (Ab) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Ab peptide is generated by proteolytic cleavage of the b-amyloid protein precursor (APP) at b- and g -sites by proteases. The long-sought b-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2)1-4. A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 14 - 9. BACE2 also cleaves APP at b-site and at a different site within Ab8. BACE2 locates on chromosome 21q22.3, the so-called Down critical region, suggesting that BACE2 and Ab may also contribute to the pathogenesis of Down syndrome.Synonyms: AEPLC, ALP56, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-secretase 2, Beta-site APP-cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1
- 基因ID
- 25825
- NCBI登录号
- NP_036237
- UniProt
- Q9Y5Z0
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