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S1PR5 抗体 (C-Term)

The 兔 多克隆 anti-S1PR5 antibody is suitable to detect S1PR5 in samples from 人. It has been validated for WB.
产品编号 ABIN264983
发货至: 中国
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Quick Overview for S1PR5 抗体 (C-Term) (ABIN264983)

抗原

See all S1PR5 抗体
S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

适用

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宿主

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克隆类型

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多克隆

标记

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This S1PR5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    C-Term

    特异性

    This antibody reacts to EDG8.

    纯化方法

    Purified

    免疫原

    Unique synthetic peptide derived from the C-terminus of the human EDG-8 protein

    亚型

    IgG
  • 应用备注

    Western Blot: 5 - 10 μg/mL, detects recombinant EDG-8 receptors at 42 kDa, Due to lowexpression of EDG receptors, we recommend use of Pierce Femto Signal substrate forwestern blot development.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原

    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

    别名

    EDG-8 / S1P5

    背景

    Endothelial Cell Differentiation Gene-8 (EDG-8) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-8 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-8 is expressed in oligodendrocytes and fibrous astrocytes in the rat brain.Synonyms: EDG8, Endothelial differentiation G-protein-coupled receptor 8, S1P receptor 5, S1PR5, SPPR-1, SPPR-2

    基因ID

    53637

    NCBI登录号

    NP_001159687

    UniProt

    Q9H228
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