S1PR5 抗体 (C-Term)
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Quick Overview for S1PR5 抗体 (C-Term) (ABIN264983)
抗原
See all S1PR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to EDG8.
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纯化方法
- Purified
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免疫原
- Unique synthetic peptide derived from the C-terminus of the human EDG-8 protein
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亚型
- IgG
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应用备注
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Western Blot: 5 - 10 μg/mL, detects recombinant EDG-8 receptors at 42 kDa, Due to lowexpression of EDG receptors, we recommend use of Pierce Femto Signal substrate forwestern blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
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别名
- EDG-8 / S1P5
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背景
- Endothelial Cell Differentiation Gene-8 (EDG-8) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-8 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-8 is expressed in oligodendrocytes and fibrous astrocytes in the rat brain.Synonyms: EDG8, Endothelial differentiation G-protein-coupled receptor 8, S1P receptor 5, S1PR5, SPPR-1, SPPR-2
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基因ID
- 53637
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NCBI登录号
- NP_001159687
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UniProt
- Q9H228
抗原
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