S1PR5 抗体 (Extracellular, N-Term)
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Quick Overview for S1PR5 抗体 (Extracellular, N-Term) (ABIN7043777)
抗原
See all S1PR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-39, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 5
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交叉反应
- 小鼠, 大鼠
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预测反应
- Rat,human - identical
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产品特性
- Anti-S1PR5/EDG8 (extracellular) Antibody (ABIN7043777, ABIN7045276 and ABIN7045277) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot analysis. It has been designed to recognize EDG8 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)KLRGARYQPGAGLRAD, corresponding to amino acid residues 24-39 of mouse S1PR5 (EDG8)
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亚型
- IgG
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anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-200) antibody
S1PR5 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-50) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Drosophila melanogaster, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (C-Term) antibodyS1PR5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 309-398) antibodyS1PR5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 大鼠, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (Internal Region) antibodyVerified S1PR5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 mg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7237280)
Blocking Peptide: (ABIN7237280)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
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别名
- S1PR5
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背景
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Synonyms: S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Lysophospholipid receptor B4, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8
Description: Sphingosine-1-phosphate receptor 5 also known as S1PR5 (EDG8) is a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).Lysophospholipids encompass a broad range of small, membrane-derived phospholipids that act as extracellular signals, mediated through specific receptors1. S1PR5 is a high-affinity cell surface S1P receptor, a member of the S1PR family. Like all GPCRs it has the classical structure of seven transmembrane domains, an extracellular N-terminus and a cytosolic C-terminal1.The signaling pathways triggered by S1P/S1P binding play a critical regulatory role in many pathophysiological processes, including skeletal muscle and nervous system degeneration, inflammation, cancer, and autoimmune disorders and hence this interaction has important implications for clinical applications and for personalized medicine2,3. Targeting S1P receptors and their downstream signaling cascades is considered as a potential treatment for cancer and various autoimmune diseases4.
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基因ID
- 94226
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NCBI登录号
- NM_030760
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UniProt
- Q91X56
抗原
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