Adenovirus E1A 抗体
Quick Overview for Adenovirus E1A 抗体 (ABIN264902)
抗原
适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- GST-EIA fusion protein recognizing a 43kD protein.
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亚型
- IgG
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应用备注
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Western Blot: 1-10 μg /mL. Positive Control: 293 cells are human embryonic kidney cells that have been transformedwith the adenovirus genes E1A and E1B, which are required for adenovirus propagation. This cell line can be used as a positive control for this antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- Adenovirus E1A (HAdV E1A) (Human Adenovirus E1A (HAdV E1A))
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物质类
- Viral Protein
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背景
- The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11 % of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105. EIA gene encodes potent onco-proteins that modify the normal transcriptional growth regulation of key cellular genes and thus alter cell cycle control.Synonyms: Adenovirus early region 1 antibody, Control protein E1A antibody, E1A antibody
抗原
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