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RPS6KA1 抗体 (C-Term)

The 兔 多克隆 anti-RPS6KA1 antibody is suitable to detect RPS6KA1 in samples from 人, 小鼠, 大鼠 和 Cow. It has been validated for WB, IP 和 EIA.
产品编号 ABIN264872
发货至: 中国
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Quick Overview for RPS6KA1 抗体 (C-Term) (ABIN264872)

抗原

See all RPS6KA1 抗体
RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

适用

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人, 小鼠, 大鼠, Cow

宿主

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克隆类型

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多克隆

标记

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This RPS6KA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody detects an ~90 kDa protein, corresponding to the molecular mass of p90 RSK1 on SDS-PAGE immunoblots.

    纯化方法

    Affinity Chromatography

    免疫原

    Human p90 RSK1 C-terminal peptide, conjugated to KLH

    亚型

    IgG
  • 应用备注

    Western blot (0.25 μg/mL). Immunoprecipitation. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    TBS, 0.09 % Sodium Azide, 50 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

    别名

    RPS6KA1

    背景

    The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1-4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signalregulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to have an important role in cellular growth control and proliferation. (1-5).Synonyms: 90 kDa ribosomal protein S6 kinase 1, MAPKAPK1A, RSK-1, RSK1, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase alpha-1, p90RSK1

    基因ID

    6195

    NCBI登录号

    NP_001006666

    UniProt

    Q15418

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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