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SOD1 抗体

There are 3+ publications for this product available. The 兔 多克隆 anti-SOD1 antibody is suitable to detect SOD1 in samples from 人, 小鼠, 大鼠 和 Cow. It has been validated for WB, IP, IHC (fro) 和 EIA.
Pubmed (3 references)
产品编号 ABIN264854
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SOD1 抗体 (ABIN264854)

抗原

See all SOD1 抗体
SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

适用

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人, 小鼠, 大鼠, Cow

宿主

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兔

克隆类型

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多克隆

标记

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This SOD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
Discover our top product SOD1 Primary Antibody

  • 特异性

    Detects a 23 kDa (Human) and 19 kDa (other species) proteins corresponding to the Molecular Mass of Cu/Zn Superoxide Dismutase (SOD) on SDS-PAGE Immunoblots.

    纯化方法

    Antigen Affinity Chromatography

    免疫原

    Rat Cu/Zn SOD

    亚型

    IgG
  • anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 1-154) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 1-154) antibody

    SOD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (C-Term) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (C-Term) antibody

    KO Validated SOD1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody

    SOD1 适用: 人, 马 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 6-100) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 6-100) antibody

    SOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody

    SOD1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody

    SOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody (APC)
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody (APC)

    SOD1 适用: 兔 WB, IHC 宿主: 豚鼠 Polyclonal APC

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody

    SOD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody

    SOD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Superoxide Dismutase 1, Soluble (SOD1) antibody
    anti-Superoxide Dismutase 1, Soluble (SOD1) antibody

    SOD1 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F5 unconjugated

  • 应用备注

    Western blot: 0.5 μg/mL was sufficient for detection of Cu/Zn SOD in 20 μg of rat braintissue extract by Colorimetric Immunoblot analysis using Goat anti-RabbitIgG-AP as the secondary antibody. (Ref.6)Immunoprecipitation. EIA (Ref.6). Immunohistochemistry on Frozen Sections (Ref.8).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用

  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.0, 0.09 % Sodium Azide, 50 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Zuber, Rappaport, Luo, Wang, Chen, Vaseva, Shi, Weissmueller, Fellmann, Fellman, Taylor, Weissenboeck, Graeber, Kogan, Vakoc, Lowe: "An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance." in: Genes & development, Vol. 25, Issue 15, pp. 1628-40, (2011) (PubMed).

    Wang, Kumagai-Braesch, Herrington, Larsson, Permert: "Increased lipid metabolism and cell turnover of MiaPaCa2 cells induced by high-fat diet in an orthotopic system." in: Metabolism: clinical and experimental, Vol. 58, Issue 8, pp. 1131-6, (2009) (PubMed).

    Huang, Lee, Kuo, Yang, Chien: "Attenuation of long-term Rhodiola rosea supplementation on exhaustive swimming-evoked oxidative stress in the rat." in: The Chinese journal of physiology, Vol. 52, Issue 5, pp. 316-24, (2009) (PubMed).

  • 抗原

    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

    别名

    Superoxide Dismutase 1 / SOD1

    背景

    Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (Ref.3). It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (Ref.2,5). In general, SODs play a major role in antioxidant defense mechanisms. (Ref.4) There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (Ref.3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (Ref.7). SOD3 can also be distinguished by its heparinbinding capacity (Ref.1).Synonyms: ALS1, CuZn-SOD, CuZnSOD, IPOA, SOD-1, Superoxide dismutase [Cu-Zn]

    基因ID

    6647

    NCBI登录号

    NP_000445

    UniProt

    P00441

    途径

    Sensory Perception of Sound, Transition Metal Ion Homeostasis
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