电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

GABBR2 抗体

GABBR2 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN264843
发货至: 中国
  • 抗原 See all GABBR2 抗体
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    适用
    • 90
    • 64
    • 59
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 105
    • 16
    克隆类型
    • 97
    • 24
    多克隆
    标记
    • 35
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This GABBR2 antibody is un-conjugated
    应用范围
    • 113
    • 52
    • 52
    • 38
    • 32
    • 16
    • 15
    • 14
    • 13
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    The antibody recognizes C-terminal of Gamma-Aminobutyric Acid (GABA) B Receptor 2 (recognized epitope: the last 23 aa). GB2 Apparent MW: ~120 kDa.
    交叉反应 (详细)
    Species reactivity (expected):Human.
    Species reactivity (tested):Mouse, Rat.
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Synthetic peptide (coupled with THG) derived from the last 23 aa of Mouse GABA B receptor 2.
    Top Product
    Discover our top product GABBR2 Primary Antibody
  • 应用备注
    Western blot: 0.6 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    别名
    GABBR2 (GABBR2 产品)
    别名
    Gpr51 antibody, GABABR2 antibody, GPR51 antibody, GPRC3B antibody, HG20 antibody, HRIHFB2099 antibody, Gb2 antibody, Gm425 antibody, GABA(B)R2 antibody, si:dkey-190l1.2 antibody, gamma-aminobutyric acid type B receptor subunit 2 antibody, gamma-aminobutyric acid (GABA) B receptor, 2 antibody, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog antibody, GABBR2 antibody, LOC100448699 antibody, gabbr2 antibody, Gabbr2 antibody, gabbr2.S antibody
    背景
    GABA B receptor is a G-protein-coupled inhibitory receptor of g-aminobutyric acid (GABA), and has important functions in brain by inhibition of adenylyl cyclase and modulation of G-protein-gated Ca2+ and K+ channels. GABA B receptor is comprised of two subunits, GB1 and GB2 with N-terminal extracellular and C-terminal intracellular domains. The GB1 subunit plays a critical role in ligand binding, whereas the GB2 subunit contains the determinants required for G-protein signaling. Multiple allosteric interactions between the two subunits are required for correct functioning of the receptor. There are two N-terminal splice variants of GB1 subunit, termed GB1a and GB1b, their expression in the central nervous system changes during the ontogenesis and differs between various regions of the brain.Synonyms: G-protein coupled receptor 51, GABA-B receptor 2, GABA-B-R2, GABBR-2, GPR51, GPRC3B, Gamma-aminobutyric acid type B receptor subunit 2, Gb2, HG20
    基因ID
    9568
    NCBI登录号
    NP_005449
    UniProt
    O75899
    途径
    cAMP Metabolic Process
You are here:
客服