KRT14 抗体
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北京 101111
Quick Overview for KRT14 抗体 (ABIN264414)
抗原
See all KRT14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts specifically with Human Cytokeratin-14 (50 kDa) by Immunoblotting. Does not react with other Cytokeratins or other proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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产品特性
- Synonyms: Cytokeratin-14, CK14, Keratin 14, K14, KRT14, Keratin Type I Cytoskeletal 14
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纯化方法
- Protein A/G Chromatography
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免疫原
- Synthetic peptide conjugated to KLH corresponding to thecarboxy terminal sequence of human cytokeratin 14(KVVSTHEQVLRTKN)Genename: KRT14
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亚型
- IgG2b
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anti-Keratin 14 (KRT14) antibody
KRT14 适用: 人 WB, IHC, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (AA 1-484) antibodyKRT14 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (AA 351-472) antibodyKRT14 适用: 人, 大鼠, 小鼠, Pig IHC, FACS, StM 宿主: 小鼠 Monoclonal KRT14-2375 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人, 大鼠, 小鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal LL002 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, Pig, 犬 WB, IHC, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RCK107 unconjugated
anti-Keratin 14 (KRT14) (AA 276-303) antibodyKRT14 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: Detects human cytokeratin 14 at 50 kDa. Immunohistochemistry (Frozen Sections): It provides a positive reaction on basal cells ofnon-keratinizing stratified epithelia, basal cells and suprabasal cells of the epidermis andgingiva, myoepithelial cells and squamous cell carcinomas. Not suitable for use in Paraffin embedded tissues.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 0.08 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- KRT14 (Keratin 14 (KRT14))
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别名
- Cytokeratin 14
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背景
- Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. Keratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. It is usually found as a heterotetramer with two molecules of keratin 5, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. Keratin 14 has been studied as a prognostic marker in breast cancer.Synonyms: CK14, Cytokeratin-14, K14, KRT14, Keratin 14, Keratin Type I Cytoskeletal 14
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基因ID
- 3861
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UniProt
- P02533
抗原
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