NAPA 抗体
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北京 101111
Quick Overview for NAPA 抗体 (ABIN264390)
抗原
See all NAPA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes an epitope within the highly conserved domain between amino acids 109 - 193 of SNAP-alpha and SNAP-beta.
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产品特性
- Synonyms: SNAP-alpha, SNAPA, NAPA, Alpha-soluble NSF attachment protein
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纯化方法
- Standard chromatographic techniques.
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免疫原
- Recombinant human alpha SNAP.
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亚型
- IgG2b
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应用备注
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Suitable for use in Western Blot: 1/5000. Positive Control: Rat brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- 20 mM Sodium Phosphate, 150 mM Sodium Chloride, 50 % Glycerol, pH 7.5
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
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别名
- SNAP alpha
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背景
- 38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide- sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. alpha-SNAP (or beta-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.Synonyms: Alpha-soluble NSF attachment protein, NAPA, SNAP-alpha, SNAPA
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基因ID
- 8775
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UniProt
- P54920
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途径
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
抗原
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