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KIT 抗体

KIT 适用: 人 FACS 宿主: 小鼠 Monoclonal NU-c-kit unconjugated
产品编号 ABIN264306
发货至: 中国
  • 抗原 See all KIT 抗体
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This KIT antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    CD117 reacts against c-kit gene product (SCF receptor).
    产品特性
    Synonyms: SCFR, KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase
    纯化方法
    Purified
    免疫原
    Immunized with transfected cells with c-kit DNA in human leukemia cells (UT-7).
    克隆位点
    NU-c-kit
    亚型
    IgG1
    Top Product
    Discover our top product KIT Primary Antibody
  • 应用备注
    Flow Cytometry. Monitoring of CD34-positive cells. Analysis of 8 % of myelomonocytes. Study of hematopoietic stem cell differentiation and proliferatiuon. Study of the c-kit gene product (SCF receptor). Study of a part of acute myeloblastic leukemia cells. Study of chronic myeloblastic leukemia cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    实验流程
    PBMC: Count the number of positive cells in peripheral blood. Add 10 µl of Mab to 50 µl suspended lymphocyte solution at 2 x 10e7. Mix gently and incubate for 15 minutes at 2-8°C.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.08 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    别名
    CD117 / C-Kit (KIT 产品)
    别名
    C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
    背景
    CD117 reacts with 8 % of myelomonocytes and 75 % of CD34-positive cells. The hematopoietic stem cells are included in this fraction and therefore, this gene product is considered to have an important function for differentiation and proliferation of hematopoietic cells. CD117 also reacts with placenta, brain, a part of acute myeloblastic leukemia cells and chronic myeloblastic leukemia cells, but not with acute lymphoblastic leukemia cells. MW is 145 kDa.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR
    基因ID
    3815
    UniProt
    P10721
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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