Prothrombin 抗体
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北京 101111
Quick Overview for Prothrombin 抗体 (ABIN264058)
抗原
See all Prothrombin (F2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody binds Prothrombin, Prethrombin 1 and fragment 2 (residues 156-271) in solid-phase ELISA. Blots Human Prothrombin in Western blot.
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产品特性
- Synonyms: Coagulation factor II
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纯化方法
- Gel filtration and Ion Exchange Chromatography
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免疫原
- Purified Human Prothrombin
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亚型
- IgG2a
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应用备注
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ELISA. Western blot. A starting range of 1-5g/mL is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with distilled water
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浓度
- 1.0 mg/mL (prior to lyophilization)
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缓冲液
- 10 mM Sodium phosphate, 0.15 M Sodium Chloride, pH 7.4 containing 0.01 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Prior to reconstitution store at -20 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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别名
- Prothrombin (F2)
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背景
- Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia.Synonyms: Coagulation factor II
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基因ID
- 2147
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UniProt
- P00734
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途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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