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Prothrombin 抗体

This anti-Prothrombin antibody is a 小鼠 单克隆 antibody detecting Prothrombin in WB 和 EIA. Suitable for 人.
产品编号 ABIN264058
发货至: 中国

Quick Overview for Prothrombin 抗体 (ABIN264058)

抗原

See all Prothrombin (F2) 抗体
Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

适用

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宿主

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小鼠

克隆类型

  • 74
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单克隆

标记

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This Prothrombin antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

BDI095
  • 特异性

    This antibody binds Prothrombin, Prethrombin 1 and fragment 2 (residues 156-271) in solid-phase ELISA. Blots Human Prothrombin in Western blot.

    产品特性

    Synonyms: Coagulation factor II

    纯化方法

    Gel filtration and Ion Exchange Chromatography

    免疫原

    Purified Human Prothrombin

    亚型

    IgG2a
  • 应用备注

    ELISA. Western blot. A starting range of 1-5g/mL is recommended.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with distilled water

    浓度

    1.0 mg/mL (prior to lyophilization)

    缓冲液

    10 mM Sodium phosphate, 0.15 M Sodium Chloride, pH 7.4 containing 0.01 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at -20 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

    别名

    Prothrombin (F2)

    背景

    Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia.Synonyms: Coagulation factor II

    基因ID

    2147

    UniProt

    P00734

    途径

    Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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