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NAPSA 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects NAPSA in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN263986
发货至: 中国
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北京 101111
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Quick Overview for NAPSA 抗体 (N-Term) (ABIN263986)

抗原

See all NAPSA 抗体
NAPSA (Napsin A Aspartic Peptidase (NAPSA))

适用

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宿主

  • 87
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小鼠

克隆类型

  • 126
  • 46
单克隆

标记

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This NAPSA antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

KCG1-1
  • 抗原表位

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    N-Term

    特异性

    Napsin A and TTF-1 reactivities were determined immunohistochemically on formalin-fixed paraffin embedded cell blocks from 50 pleural effusion (5 mesotheliomas, 10 mesothelial proliferations, 12 pulmonary, and 23 nonpulmonary metastases). TTF-1 and Napsin A were positive in 8/12 and 10/12 pulmonary adenocarcinomas, respectively. The specificity of this antibody for primary lung adenocarcinoma is 47 out of 58 (81 %), primary lesions were positive. This antibody may be a useful tool as a tumor marker for primary lung adenocarcinoma.

    产品特性

    Synonyms: NAPSA, NAP1, Napsin-1, Aspartyl protease 4, TA01/TA02

    纯化方法

    Purified

    免疫原

    Synthetic peptide from N terminus of Human Napsin A

    亚型

    IgG1
  • 应用备注

    Immunohistochemistry on Paraffin Sections: Use at 1/50-1/100 dilution in an ABC method(30 minutes at room temperature). However, depending upon the fixation conditions andthe staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Lung Adenocarcinoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    NAPSA (Napsin A Aspartic Peptidase (NAPSA))

    别名

    Napsin-A

    背景

    Napsin is found in two isoforms, A and B, with highly homologous gene sequences. Napsin A has a molecular weight of 35.0 kDa and is also known as TA02. Napsin A is an aspartic proteinase which is expressed in the lung and involved in processing surfactant protein B (SP-B). It is also expressed in the kidney.Synonyms: Aspartyl protease 4, NAP1, NAPSA, Napsin-1, TA01/TA02

    基因ID

    9476

    UniProt

    O96009

    途径

    Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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